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Recombinant Human NR2C2AP protein (N-His) | High Purity, Certified | Reliable Supplier

Recombinant Human NR2C2AP protein (N-His) is a high-purity biochemical reagent expressed in E. coli, featuring a 6x His-tag at the N-terminus for streamlined purification and detection. This 15.9 kDa protein, also known as TRA16, functions as a critical co-regulator that represses TR4-mediated transactivation by modulating DNA-binding affinity. It is an essential tool for researchers studying nuclear receptor signaling, gene expression regulation, and oncogenic pathways in non-small cell lung carcinoma. With a purity exceeding 85%, this lyophilized protein ensures reliable performance in Western blotting, ELISA, and functional assays investigating cell-fate determination, apoptosis, and transcriptional fine-tuning across diverse human tissues.

Catalog No.: 5086928
Unit Size
Product Category Recombinant Proteins

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High-Purity Recombinant Human NR2C2AP Protein (N-His): A Catalyst for Molecular Research

1. Introduction

In the rapidly advancing landscape of molecular biology and drug discovery, high-purity Recombinant Human NR2C2AP protein (N-His) has emerged as an indispensable tool for understanding nuclear receptor signaling pathways. As biotechnology and pharmaceutical sectors continue to prioritize precision and reproducible data, the demand for high-fidelity protein reagents has reached an all-time high. This recombinant protein represents the intersection of scientific innovation and functional proteomics, providing researchers with the structural integrity required to unlock new insights into gene regulation and cellular homeostasis. For research institutions and industrial clients aiming for breakthrough discoveries, this protein serves as a cornerstone for high-impact biochemical assays.

2. Product Overview

The Recombinant Human NR2C2AP protein (Nuclear Receptor 2C2-Associated Protein) is a highly specialized reagent produced through advanced recombinant DNA technology. This specific version features an N-terminal Polyhistidine (His) tag, facilitating efficient purification and detection in various experimental setups. The protein is expressed in high-performance systems and purified to rigorous standards, typically exceeding 90% purity as determined by SDS-PAGE. NR2C2AP is known for its critical role in modulating the activity of nuclear receptors, particularly NR2C2 (TR4), which is vital in embryonic development and metabolic regulation. Our formulation ensures that the protein maintains its native conformational state, meeting international laboratory benchmarks for bioactivity and consistency.

3. Key Features and Benefits

  • Exceptional Purity and Bioactivity: With high-purity levels, this protein minimizes non-specific interactions, ensuring that research chemicals provide clear, accurate, and reproducible results in sensitive assays.
  • Efficient N-His Tagging: The N-terminal His-tag allows for easy immobilization on nickel-based resins and simplified detection using anti-His antibodies, making it compatible with high-throughput screening.
  • High Stability and Solubility: Engineered for robustness, the protein remains stable across various buffer conditions, reducing experimental variability and supporting long-term laboratory goals.
  • Standardized Quality Control: Each batch undergoes stringent validation to ensure consistent molecular weight and folding, aligning with the quality management systems required by pharmaceutical B2B clients.
  • Eco-Friendly Production: Utilizing optimized cell-based expression systems, the manufacturing process adheres to modern sustainability initiatives by reducing chemical waste and energy consumption.

4. Applications Across Industries

The Recombinant Human NR2C2AP protein (N-His) finds extensive use across several high-stakes sectors. In the pharmaceutical industry, it is utilized as a target in drug-protein interaction studies and ligand binding assays. Diagnostic labs and healthcare facilities employ this protein in the development of novel biomarkers for metabolic disorders. In academic research, it is a vital reagent for protein-protein interaction (PPI) studies, particularly in investigating nuclear receptor co-regulators. Furthermore, the biotechnology sector leverages this protein in the development of cell-based assays and proteomic profiling, ensuring that industrial production facilities maintain the highest level of scientific accuracy.

5. Why Choose This Product

When you buy Recombinant Human NR2C2AP protein (N-His) from a premier biochemical distributor, you are choosing a partner dedicated to scientific excellence. Our product stands out due to its consistent supply chain and full compliance with local and international import/export standards. We provide comprehensive technical support to assist with specialized protocols, ensuring that our laboratory reagents integrate seamlessly into your existing workflows. Trusted by top-tier research universities and global pharmaceutical giants, our protein reagents provide the precision necessary for high-impact clinical and industrial studies.

6. Brand Credibility and Assurance

Our commitment to the scientific community is backed by years of expertise in protein engineering and supply. As a leading Recombinant Human NR2C2AP protein (N-His) supplier, we operate under strict adherence to global quality standards. We offer customer-focused services, including bulk availability for large-scale screenings and prompt worldwide delivery to ensure your project timelines are met. Our technical team provides professional consultation, helping you select the right reagents for your specific research needs, all backed by our unparalleled brand assurance.

7. Call to Action

Elevate your research and development projects with the precision of our high-purity Recombinant Human NR2C2AP protein (N-His). Whether you are investigating fundamental cellular pathways or developing the next generation of therapeutics, our team is ready to provide the high-quality reagents you require. Contact us today for a custom quote, bulk supply inquiry, or technical consultation. Trust in our reliability to drive your next scientific breakthrough.

FAQ

What is the recommended storage for Recombinant Human NR2C2AP protein?
The protein should be stored at -20°C to -80°C for long-term stability. Avoid repeated freeze-thaw cycles by creating single-use aliquots upon receipt.
What is the purpose of the N-terminal His-tag?
The His-tag allows for rapid purification using immobilized metal affinity chromatography (IMAC) and provides a convenient handle for detection in Western blotting or ELISA.
Can this protein be used in cell-based assays?
Yes, it is suitable for various in vitro assays, including protein-protein interaction studies and competitive binding experiments.
Is this product available for bulk purchase?
Yes, we offer flexible scaling options from microgram quantities for pilot studies to milligram quantities for industrial-scale research.

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At Royal Vista Trading, we are committed to building long-term partnerships by delivering high-quality products, competitive pricing, and exceptional service. Whether you need chemical raw materials, industrial solvents, or specialized reagents, we are your trusted sourcing partner.

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