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MRTF-A Polyclonal Antibody is developed by immunizing animals with a synthetic peptide corresponding to the N-terminal region of human MRTF-A protein. This antibody is purified by protein A and peptide affinity chromatography, typically provided as a liquid in PBS containing glycerol and BSA. MRTF-A (Myocardin-Related Transcription Factor A, also known as MKL1) is a key regulator of the MRTFA-SRF complex, binding to G-actin. The antibody is used for detecting MKL1/MRTF-A, with tested applications often including Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence/Immunocytochemistry (IF/ICC), and ELISA, reacting with human, mouse, and rat species.
| Catalog No.: | 4012856 |
| Unit Size | |
| Product Category | Primary Antibody |
In the dynamic global landscape of life sciences, precise regulation of gene expression is fundamental to understanding cellular processes, disease mechanisms, and therapeutic targets. The MRTF-A Polyclonal Antibody stands as an indispensable biochemical tool, ensuring high-fidelity detection and characterization of the Myocardin-Related Transcription Factor A (MRTF-A), also known as MKL1. This premium-quality reagent is vital for the rapidly growing biotechnology, pharmaceuticals, and healthcare sectors, where accurate insight into actin-dependent signaling is critical. Utilizing this specific antibody aligns research innovation with scientific advancement, providing the reliable data required for breakthroughs in cellular and molecular biology.
The MRTF-A Polyclonal Antibody is a high-purity, affinity-purified immunoglobulin designed for the specific detection of the MRTF-A protein. MRTF-A is a crucial regulator of serum response factor (SRF)-dependent transcription, binding to G-actin via its RPEL repeats to modulate the MRTF-A-SRF complex activity. This function is often regulated by filamentous actin (F-actin) dynamics within the nucleus. Our antibody is produced by immunizing animals with a synthetic peptide corresponding to a specific region of the human MKL1/MRTF-A protein (as suggested by search results). The resulting antibody is rigorously purified to meet stringent international biochemical quality benchmarks, ensuring lot-to-lot consistency and compliance with demanding laboratory standards. This robust formulation ensures minimal cross-reactivity and exceptional signal-to-noise ratios, crucial for both quantitative and qualitative assays.
The MRTF-A Polyclonal Antibody is indispensable for researchers focused on understanding mechanotransduction, cell motility, and tissue development. In academic research, it is used to investigate the role of MRTF-A in modulating cytoskeletal dynamics and gene expression in various cell types. The pharmaceutical manufacturing sector utilizes this reagent for screening compounds that target the MRTF-A pathway in conditions like fibrosis, cancer, and cardiovascular disease, making it a critical tool in clinical studies. Furthermore, as a specialized research chemical, it supports advanced diagnostics by enabling detailed cellular analysis in diagnostic labs and research institutions globally.
Choosing our MRTF-A Polyclonal Antibody supplier means partnering with a source committed to quality and precision. We stand apart through our guarantee of consistent supply and adherence to rigorous quality management systems (such as ISO standards). This antibody is trusted by leading laboratories and institutions across the globe for its exceptional precision and reliability. We ensure that every batch provides the reproducible results necessary for impactful scientific publications and critical drug development milestones.
Our commitment to quality is upheld by our deep expertise as a trusted biochemical distributor. We adhere to global standards, providing high-purity, certified reagents designed for demanding industrial and research applications. We offer comprehensive customer-focused services, including prompt worldwide delivery and professional consultation for specialized use. Our bulk availability options ensure continuous and seamless workflow for large-scale projects, reinforcing our role as a reliable partner in scientific advancement.
Accelerate your research into cellular mechanics and gene regulation today. For reliable detection of the MRTF-A protein, choose the proven quality of our MRTF-A Polyclonal Antibody. Contact us now for purchase, bulk supply options, or professional consultation. We deliver the precision and value essential for the evolving biochemical industry. Dont wait, buy MRTF-A Polyclonal Antibody and ensure the success of your next critical experiment.
At Royal Vista Trading, we are committed to building long-term partnerships by delivering high-quality products, competitive pricing, and exceptional service. Whether you need chemical raw materials, industrial solvents, or specialized reagents, we are your trusted sourcing partner.
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